Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 3 Researches
7.7
USERS' SCORE
Good
Based on 31 Reviews
8.1
Supplement Facts
Serving Size: 1 Vegetarian Capsule
Amount Per Serving
%DV
Vitamin E (as D-alpha tocopheryl succinate)
20.1 mg
134%
Selenium (as Se-Methyl L-Selenocysteine, L-selenomethionine (yeast-free), sodium selenite)
200 mcg
364%
Top Medical Research Studies
8
We studied how selenium-polysaccharides (Se-TP) from green tea could improve chronic fatigue syndrome (CFS) in a rat model. Our experiments revealed that Se-TP significantly enhanced levels of certain substances related to fatigue, indicating improved overall condition. However, while the treatment showed promise in restoring some metabolic markers, the overall efficacy in CFS management remains to be fully affirmed. The changes observed were tied to metabolic pathways involved in steroid hormone biosynthesis and other critical processes.
Read More
8
We explored how sweet corn cob polysaccharide selenium nanoparticles (U-SCPSeNPs) might help alleviate symptoms of chronic fatigue syndrome (CFS). In this study, we used mouse models to test the effects of these nanoparticles, which were created using an ultrasound-assisted method.
While the U-SCPSeNPs showed promise in improving energy production and enhancing gut microbiota, the results indicated no significant improvement in clinical symptoms of CFS. Thus, while interesting, the potential of selenium treatment for CFS remains unproven.
While the U-SCPSeNPs showed promise in improving energy production and enhancing gut microbiota, the results indicated no significant improvement in clinical symptoms of CFS. Thus, while interesting, the potential of selenium treatment for CFS remains unproven.
Read More
7
CoQ10 and selenium may benefit ME/CFS
We explored whether combining Coenzyme Q10 and selenium could improve outcomes for individuals with chronic fatigue syndrome (ME/CFS). In this study, 27 patients took an oral supplement for 8 weeks. While we noted improvements in overall fatigue severity and quality of life, sleep disturbances did not show any significant change. Additionally, we found increased antioxidant capacity and decreased inflammatory markers, indicating potential benefits. However, other key biomarkers did not show significant changes. Overall, this suggests that long-term supplementation might help some symptoms in ME/CFS.
Read More
Most Useful Reviews
9
Enhanced well-being
57 people found this helpful
After tests revealed low levels of selenium and iodine, I began taking selenium. Within two weeks, my overall wellbeing improved significantly, and fatigue decreased. It also reduced heavy metal levels in my body, and I felt revitalised.
Read More
9
Boosted energy
11 people found this helpful
After being diagnosed with Hashimoto's, I opted for a natural approach, avoiding prescription thyroid medication. Going gluten-free and taking selenium improved my chronic fatigue syndrome and gave me back my energy. I've been on this supplement for nearly a year now, and my energy has returned, allowing me to run again! My blood work is better than in the past decade.
Read More
9
Increased energy
4 people found this helpful
I took this complex based on a nutritionist's advice to address hypothyroidism, which had left me fatigued and weak. Almost immediately, I felt better; my chronic fatigue syndrome lessened, hair loss reduced, and my heartbeat stabilised. I recommend this essential vitamin for improved bodily function and well-being.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 3 Researches
7.7
- All Researches
8
We explored how sweet corn cob polysaccharide selenium nanoparticles (U-SCPSeNPs) might help alleviate symptoms of chronic fatigue syndrome (CFS). In this study, we used mouse models to test the effects of these nanoparticles, which were created using an ultrasound-assisted method.
While the U-SCPSeNPs showed promise in improving energy production and enhancing gut microbiota, the results indicated no significant improvement in clinical symptoms of CFS. Thus, while interesting, the potential of selenium treatment for CFS remains unproven.
While the U-SCPSeNPs showed promise in improving energy production and enhancing gut microbiota, the results indicated no significant improvement in clinical symptoms of CFS. Thus, while interesting, the potential of selenium treatment for CFS remains unproven.
Read More
8
We studied how selenium-polysaccharides (Se-TP) from green tea could improve chronic fatigue syndrome (CFS) in a rat model. Our experiments revealed that Se-TP significantly enhanced levels of certain substances related to fatigue, indicating improved overall condition. However, while the treatment showed promise in restoring some metabolic markers, the overall efficacy in CFS management remains to be fully affirmed. The changes observed were tied to metabolic pathways involved in steroid hormone biosynthesis and other critical processes.
Read More
7
CoQ10 and selenium may benefit ME/CFS
We explored whether combining Coenzyme Q10 and selenium could improve outcomes for individuals with chronic fatigue syndrome (ME/CFS). In this study, 27 patients took an oral supplement for 8 weeks. While we noted improvements in overall fatigue severity and quality of life, sleep disturbances did not show any significant change. Additionally, we found increased antioxidant capacity and decreased inflammatory markers, indicating potential benefits. However, other key biomarkers did not show significant changes. Overall, this suggests that long-term supplementation might help some symptoms in ME/CFS.
Read More
User Reviews
USERS' SCORE
Good
Based on 31 Reviews
8.1
- All Reviews
- Positive Reviews
- Negative Reviews
9
Enhanced well-being
57 people found this helpful
After tests revealed low levels of selenium and iodine, I began taking selenium. Within two weeks, my overall wellbeing improved significantly, and fatigue decreased. It also reduced heavy metal levels in my body, and I felt revitalised.
Read More
9
Boosted energy
11 people found this helpful
After being diagnosed with Hashimoto's, I opted for a natural approach, avoiding prescription thyroid medication. Going gluten-free and taking selenium improved my chronic fatigue syndrome and gave me back my energy. I've been on this supplement for nearly a year now, and my energy has returned, allowing me to run again! My blood work is better than in the past decade.
Read More
9
Increased energy
4 people found this helpful
I took this complex based on a nutritionist's advice to address hypothyroidism, which had left me fatigued and weak. Almost immediately, I felt better; my chronic fatigue syndrome lessened, hair loss reduced, and my heartbeat stabilised. I recommend this essential vitamin for improved bodily function and well-being.
Read More
9
Enhanced vitality
3 people found this helpful
Approaching forty, I realised I needed support for my chronic fatigue syndrome. After starting selenium, my fatigue diminished, sleep quality improved, and I felt energised and less prone to colds. Selenium strengthens blood vessels and enhances overall health, and I'm feeling so much better.
Read More
9
Restored selenium levels
1 people found this helpful
This supplement helped me restore my selenium levels over two months. My husband experienced relief from chronic fatigue syndrome within just two days of using it.
Read More
Frequently Asked Questions
7.5
Mood improvement
2 people found this helpful
This supplement aids in normalising thyroid function, thereby addressing my chronic fatigue syndrome. After just four days, my mood improved significantly, and I felt like myself again within a week. Although the smell and taste aren't pleasant, the capsules are easy to swallow, and I recommend consulting a specialist before use.
9
Mood improvement
After four days of taking selenium, my mood improved significantly. My health returned to normal after a week, particularly after chronic nasal inflammation.
9
Enhanced well-being
57 people found this helpful
After tests revealed low levels of selenium and iodine, I began taking selenium. Within two weeks, my overall wellbeing improved significantly, and fatigue decreased. It also reduced heavy metal levels in my body, and I felt revitalised.
7.5
Improved mood
215 people found this helpful
Selenium is a vital mineral that supports the endocrine, immune, and reproductive systems. It acts as an antioxidant and, alongside vitamin E, shields the body from free radicals and promotes normal cell growth. After two weeks of taking it, my chronic fatigue syndrome diminished significantly, my mood improved, and skin peeling reduced. I highly recommend it!
10
Strengthened immunity
I've been taking the super complex of selenium with vitamin E for a month, and the results are impressive! I've noticed improved skin condition, increased energy, and disappearance of fatigue, along with a stronger immune system.
9
Boosted energy
11 people found this helpful
After being diagnosed with Hashimoto's, I opted for a natural approach, avoiding prescription thyroid medication. Going gluten-free and taking selenium improved my chronic fatigue syndrome and gave me back my energy. I've been on this supplement for nearly a year now, and my energy has returned, allowing me to run again! My blood work is better than in the past decade.
9
Increased energy
4 people found this helpful
I took this complex based on a nutritionist's advice to address hypothyroidism, which had left me fatigued and weak. Almost immediately, I felt better; my chronic fatigue syndrome lessened, hair loss reduced, and my heartbeat stabilised. I recommend this essential vitamin for improved bodily function and well-being.
7.5
Improved state of health
I took it daily, benefiting from the combined effects of selenium and vitamin E. Within four days, my mood brightened, and my health stabilised despite chronic fatigue syndrome.
7.5
Reduced fatigue
This is excellent; I take it alongside iodine for better absorption. After starting, I experienced a noticeable increase in cheerfulness and no longer feel fatigue as before.
7.5
Feeling better
8 people found this helpful
A nutritionist recommended selenium for my autoimmune thyroid issues. After starting this along with other vitamins, the symptoms of my chronic fatigue syndrome, like fatigue and immune weakness, began to improve. The capsules are easy to take, and I’m noticing positive changes in my condition as I await my next test results.
8
We explored how sweet corn cob polysaccharide selenium nanoparticles (U-SCPSeNPs) might help alleviate symptoms of chronic fatigue syndrome (CFS). In this study, we used mouse models to test the effects of these nanoparticles, which were created using an ultrasound-assisted method.
While the U-SCPSeNPs showed promise in improving energy production and enhancing gut microbiota, the results indicated no significant improvement in clinical symptoms of CFS. Thus, while interesting, the potential of selenium treatment for CFS remains unproven.
While the U-SCPSeNPs showed promise in improving energy production and enhancing gut microbiota, the results indicated no significant improvement in clinical symptoms of CFS. Thus, while interesting, the potential of selenium treatment for CFS remains unproven.
7
CoQ10 and selenium may benefit ME/CFS
We explored whether combining Coenzyme Q10 and selenium could improve outcomes for individuals with chronic fatigue syndrome (ME/CFS). In this study, 27 patients took an oral supplement for 8 weeks. While we noted improvements in overall fatigue severity and quality of life, sleep disturbances did not show any significant change. Additionally, we found increased antioxidant capacity and decreased inflammatory markers, indicating potential benefits. However, other key biomarkers did not show significant changes. Overall, this suggests that long-term supplementation might help some symptoms in ME/CFS.
8
We studied how selenium-polysaccharides (Se-TP) from green tea could improve chronic fatigue syndrome (CFS) in a rat model. Our experiments revealed that Se-TP significantly enhanced levels of certain substances related to fatigue, indicating improved overall condition. However, while the treatment showed promise in restoring some metabolic markers, the overall efficacy in CFS management remains to be fully affirmed. The changes observed were tied to metabolic pathways involved in steroid hormone biosynthesis and other critical processes.
References
- Wang J, Wang X, Xiu W, Li C, Yu S, et al. Ultrasound-assisted preparation of sweet corn cob polysaccharide selenium nanoparticles alleviates symptoms of chronic fatigue syndrome. Food Funct. 2025;16:133. doi:10.1039/d4fo04195j
- Castro-Marrero J, Domingo JC, Cordobilla B, Ferrer R, Giralt M, et al. Does Coenzyme Q10 Plus Selenium Supplementation Ameliorate Clinical Outcomes by Modulating Oxidative Stress and Inflammation in Individuals with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome?. Antioxid Redox Signal. 2022;36:729. doi:10.1089/ars.2022.0018
- Shao C, Song J, Zhao S, Jiang H, Wang B, et al. Therapeutic Effect and Metabolic Mechanism of A Selenium-Polysaccharide from Green Tea on Chronic Fatigue Syndrome. Polymers (Basel). 2018;10. doi:10.3390/polym10111269
